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Emotionally Vulnerable Subtype of Internet Gaming Disorder: Measuring and Exploring the Pathology of Problematic Generative AI Use
Sun, Haocan, Wu, Di, Liu, Weizi, Yu, Guoming, Yao, Mike
Concerns over the potential over-pathologization of generative AI (GenAI) use and the lack of conceptual clarity surrounding GenAI addiction call for empirical tools and theoretical refinement. This study developed and validated the PUGenAIS-9 (Problematic Use of Generative Artificial Intelligence Scale-9 items) and examined whether PUGenAIS reflects addiction-like patterns under the Internet Gaming Disorder (IGD) framework. Using samples from China and the United States (N = 1,508), we conducted confirmatory factor analysis and identified a robust 31-item structure across nine IGD-based dimensions. We then derived the PUGenAIS-9 by selecting the highest-loading items from each dimension and validated its structure in an independent sample (N = 1,426). Measurement invariance tests confirmed its stability across nationality and gender. Person-centered (latent profile analysis) and variable-centered (network analysis) approaches revealed a 5-10% prevalence rate, a symptom network structure similar to IGD, and predictive factors related to psychological distress and functional impairment. These findings indicate that PUGenAI shares features of the emotionally vulnerable subtype of IGD rather than the competence-based type. These results support using PUGenAIS-9 to identify problematic GenAI use and show the need to rethink digital addiction with an ICD (infrastructures, content, and device) model. This keeps addiction research responsive to new media while avoiding over-pathologizing.
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Towards Interpretable Renal Health Decline Forecasting via Multi-LMM Collaborative Reasoning Framework
Wu, Peng-Yi, Huang, Pei-Cing, Chen, Ting-Yu, Ku, Chantung, Lin, Ming-Yen, Kang, Yihuang
Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown strong potential in clinical prediction tasks due to their ability to process visual and textual information. However, challenges related to deployment cost, data privacy, and model reliability hinder their adoption. In this study, we propose a collaborative framework that enhances the performance of open-source LMMs for eGFR forecasting while generating clinically meaningful explanations. The framework incorporates visual knowledge transfer, abductive reasoning, and a short-term memory mechanism to enhance prediction accuracy and interpretability. Experimental results show that the proposed framework achieves predictive performance and interpretability comparable to proprietary models. It also provides plausible clinical reasoning processes behind each prediction. Our method sheds new light on building AI systems for healthcare that combine predictive accuracy with clinically grounded interpretability.
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